MiR-141 suppresses the migration and invasion of HCC cells by targeting Tiam1.

BACKGROUND: We have demonstrated that T lymphoma invasion and metastasis 1 (Tiam1) gene is associated with the poor prognosis of patients with hepatocellular carcinoma (HCC), and we used a computational approach to identify miR-141 as a Tiam1-targeting microRNA (miRNA). Here, we explored the functio...

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Bibliographic Details
Main Authors: Ying Liu, Yi Ding, Jing Huang, Shuang Wang, Wen Ni, Jian Guan, Qisheng Li, Yuqin Zhang, Yanqing Ding, Bin Chen, Longhua Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923786?pdf=render