Primary MALT Type Skin Lymphoma—Is ‘Wait and See’ a Possible Strategy?

• Main Authors: Florentina Silvia Delli, Thomas Zaraboukas, Ioanna Mandekou-Lefaki
• Format: Article
• Language: English
• Published: SAGE Publishing 2008-01-01
• Series: Clinical Medicine Insights: Oncology
• Online Access: https://doi.org/10.4137/CMO.S336

Primary cutaneous lymphomas are the second most common site of extranodal non-Hodgkin lymphoma. A specifically type named extranodal marginal zone B-cell lymphomas are indolent low-grade neoplasma. We report a case of a 42-year-old white man with multiple subcutaneous tumors located on the trunk and neck. The histopathological exam showed a non-epidermotropic, dense lymphocytic infiltrate. Histologic, immunohistochemical and cytologenetic analysis diagnosed primary cutaneous B-cell lymphoma MALT type. Investigation for other extranodal MALT lymphoma gastrointestinal tract, lung, salivary and thyroid glands was negative. The patient refused radiotherapy, but he accepted every 6 months close follow-up. Over a seven years period, we noticed a progressively disappearance of the skin lesions. The necessity of aggressive treatment of this disease with excellent prognosis is discussed. The treatment necessity of primary cutaneous B-cell lymphoma MALT type is discussed.