Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

Methods to prepare 1,2-diamines are desirable due the importance of these compounds as drug scaffolds and organic ligands for metals. Here, the authors report an electrochemical metal-free 1,2- diamination of aryl alkenes with sulfamides to 1,2-diamines with excellent diastereoselectivity.

Bibliographic Details
Main Authors:	Chen-Yan Cai, Xiao-Min Shu, Hai-Chao Xu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-13024-5

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spelling	doaj-b59a4a032dcb465182ca19b66a7eb4a32021-05-11T11:58:06ZengNature Publishing GroupNature Communications2041-17232019-10-011011710.1038/s41467-019-13024-5Practical and stereoselective electrocatalytic 1,2-diamination of alkenesChen-Yan Cai0Xiao-Min Shu1Hai-Chao Xu2State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen UniversityState Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen UniversityState Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen UniversityMethods to prepare 1,2-diamines are desirable due the importance of these compounds as drug scaffolds and organic ligands for metals. Here, the authors report an electrochemical metal-free 1,2- diamination of aryl alkenes with sulfamides to 1,2-diamines with excellent diastereoselectivity.https://doi.org/10.1038/s41467-019-13024-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Chen-Yan Cai Xiao-Min Shu Hai-Chao Xu
spellingShingle	Chen-Yan Cai Xiao-Min Shu Hai-Chao Xu Practical and stereoselective electrocatalytic 1,2-diamination of alkenes Nature Communications
author_facet	Chen-Yan Cai Xiao-Min Shu Hai-Chao Xu
author_sort	Chen-Yan Cai
title	Practical and stereoselective electrocatalytic 1,2-diamination of alkenes
title_short	Practical and stereoselective electrocatalytic 1,2-diamination of alkenes
title_full	Practical and stereoselective electrocatalytic 1,2-diamination of alkenes
title_fullStr	Practical and stereoselective electrocatalytic 1,2-diamination of alkenes
title_full_unstemmed	Practical and stereoselective electrocatalytic 1,2-diamination of alkenes
title_sort	practical and stereoselective electrocatalytic 1,2-diamination of alkenes
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-10-01
description	Methods to prepare 1,2-diamines are desirable due the importance of these compounds as drug scaffolds and organic ligands for metals. Here, the authors report an electrochemical metal-free 1,2- diamination of aryl alkenes with sulfamides to 1,2-diamines with excellent diastereoselectivity.
url	https://doi.org/10.1038/s41467-019-13024-5
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Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

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