| Summary: | Objective: To explore the risk factors of rebleeding after endoscopic therapy in patients with
non-variceal upper gastrointestinal bleeding (NVUGIB). Methods: A total of 254 patients
with NVUGIB who were admitted in our hospital for endoscopic therapy were included in the
study and divided into the rebleeding group (n=76) and non-bleeding group (n=178) according
to whether there was rebleeding or not. The general materials and laboratory examination
results in the two groups were recorded. The single factor and multiple factor logistic
regression analysis was used to evaluate the risk factors of rebleeding after endoscopic therapy
in patients with NVUGIB. Results: The single factor analysis showed that the comparison
of heart rate after admission >100 times/min, upper gastrointestinal tumor bleeding, grade
Ⅰa bleeding, initial endoscopic therapy time>24 h, bleeding lesion diameter>2 cm, single
endoscopic therapy method, amount of bleeding>800 mL, sequential PPIs insufficiency, and
PT≥17 s between the two groups was statistically significant. The multiple factor logistic
regression analysis showed that grade Ⅰa bleeding, malignant tumor bleeding, bleeding lesion
diameter>2 cm, single endoscopic therapy method, and sequential PPIs insufficiency were
significantly positively correlated with the occurrence of rebleeding after endoscopic therapy in
patients with NVUGIB. Conclusions: Grade Ⅰa bleeding, malignant tumor bleeding, bleeding
lesion diameter>2 cm, sequential PPIs insufficiency, and PT≥17 s are the independent risk
factors for developing rebleeding after endoscopic therapy in patients with NVUGIB.
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