Down-Regulation of MiR-181c-5p Promotes Epithelial-to-Mesenchymal Transition in Laryngeal Squamous Cell Carcinoma via Targeting SERPINE1

Down-Regulation of MiR-181c-5p Promotes Epithelial-to-Mesenchymal Transition in Laryngeal Squamous Cell Carcinoma via Targeting SERPINE1

Laryngeal squamous cell carcinoma (LSCC) arises from the squamous epithelium of the larynx and is associated with a high incidence of cervical lymph node metastasis. MicroRNAs (miRNAs) play a crucial role in the epigenetic regulation of cellular biological processes, including cancer metastasis. How...

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Bibliographic Details
Main Authors: Xin Li, Ping Wu, Yaoyun Tang, Yuhua Fan, Yalan Liu, Xing Fang, Wei Wang, Suping Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
miRNA
mRNA
laryngeal squamous cell carcinoma
epithelial-to-mesenchymal transition
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.544476/full

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