Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers

The discovery of reprogramming and generation of human-induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine and opened new opportunities in cell replacement therapies. While generation of iPSCs represents a significant breakthrough, the clinical relevance of i...

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Bibliographic Details
Main Authors: Mehdi Shafa, Fan Yang, Thomas Fellner, Mahendra S. Rao, Behnam Ahmadian Baghbaderani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2018.00069/full