Research status of biodegradable metals designed for oral and maxillofacial applications: A review
The oral and maxillofacial regions have complex anatomical structures and different tissue types, which have vital health and aesthetic functions. Biodegradable metals (BMs) is a promising bioactive materials to treat oral and maxillofacial diseases. This review summarizes the research status and fu...
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Format: | Article |
Language: | English |
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KeAi Communications Co., Ltd.
2021-11-01
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Series: | Bioactive Materials |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X21000153 |
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Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dandan Xia Fan Yang Yufeng Zheng Yunsong Liu Yongsheng Zhou |
spellingShingle |
Dandan Xia Fan Yang Yufeng Zheng Yunsong Liu Yongsheng Zhou Research status of biodegradable metals designed for oral and maxillofacial applications: A review Bioactive Materials Biodegradable metals Oral and maxillofacial region Bone fracture Bone fixation Bone defect Guided bone regeneration |
author_facet |
Dandan Xia Fan Yang Yufeng Zheng Yunsong Liu Yongsheng Zhou |
author_sort |
Dandan Xia |
title |
Research status of biodegradable metals designed for oral and maxillofacial applications: A review |
title_short |
Research status of biodegradable metals designed for oral and maxillofacial applications: A review |
title_full |
Research status of biodegradable metals designed for oral and maxillofacial applications: A review |
title_fullStr |
Research status of biodegradable metals designed for oral and maxillofacial applications: A review |
title_full_unstemmed |
Research status of biodegradable metals designed for oral and maxillofacial applications: A review |
title_sort |
research status of biodegradable metals designed for oral and maxillofacial applications: a review |
publisher |
KeAi Communications Co., Ltd. |
series |
Bioactive Materials |
issn |
2452-199X |
publishDate |
2021-11-01 |
description |
The oral and maxillofacial regions have complex anatomical structures and different tissue types, which have vital health and aesthetic functions. Biodegradable metals (BMs) is a promising bioactive materials to treat oral and maxillofacial diseases. This review summarizes the research status and future research directions of BMs for oral and maxillofacial applications. Mg-based BMs and Zn-based BMs for bone fracture fixation systems, and guided bone regeneration (GBR) membranes, are discussed in detail. Zn-based BMs with a moderate degradation rate and superior mechanical properties for GBR membranes show great potential for clinical translation. Fe-based BMs have a relatively low degradation rate and insoluble degradation products, which greatly limit their application and clinical translation. Furthermore, we proposed potential future research directions for BMs in the oral and maxillofacial regions, including 3D printed BM bone scaffolds, surface modification for BMs GBR membranes, and BMs containing hydrogels for cartilage regeneration, soft tissue regeneration, and nerve regeneration. Taken together, the progress made in the development of BMs in oral and maxillofacial regions has laid a foundation for further clinical translation. |
topic |
Biodegradable metals Oral and maxillofacial region Bone fracture Bone fixation Bone defect Guided bone regeneration |
url |
http://www.sciencedirect.com/science/article/pii/S2452199X21000153 |
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AT dandanxia researchstatusofbiodegradablemetalsdesignedfororalandmaxillofacialapplicationsareview AT fanyang researchstatusofbiodegradablemetalsdesignedfororalandmaxillofacialapplicationsareview AT yufengzheng researchstatusofbiodegradablemetalsdesignedfororalandmaxillofacialapplicationsareview AT yunsongliu researchstatusofbiodegradablemetalsdesignedfororalandmaxillofacialapplicationsareview AT yongshengzhou researchstatusofbiodegradablemetalsdesignedfororalandmaxillofacialapplicationsareview |
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1721209906257723392 |
spelling |
doaj-b5674e5d3ed44b73b71c4fca89f728c12021-08-12T04:35:04ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-11-0161141864208Research status of biodegradable metals designed for oral and maxillofacial applications: A reviewDandan Xia0Fan Yang1Yufeng Zheng2Yunsong Liu3Yongsheng Zhou4Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Beijing Key Laboratory of Digital Stomatology, National Medical Products Administration, Key Laboratory for Dental Materials, Research Center of Engineering and Technology for Digital Dentistry, Ministry of Health, Beijing, 100081, China; Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, 100871, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Beijing Key Laboratory of Digital Stomatology, National Medical Products Administration, Key Laboratory for Dental Materials, Research Center of Engineering and Technology for Digital Dentistry, Ministry of Health, Beijing, 100081, ChinaNational Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Beijing Key Laboratory of Digital Stomatology, National Medical Products Administration, Key Laboratory for Dental Materials, Research Center of Engineering and Technology for Digital Dentistry, Ministry of Health, Beijing, 100081, China; Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, 100871, China; Corresponding author. Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China.Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Beijing Key Laboratory of Digital Stomatology, National Medical Products Administration, Key Laboratory for Dental Materials, Research Center of Engineering and Technology for Digital Dentistry, Ministry of Health, Beijing, 100081, China; Co-corresponding author. Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China.Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Beijing Key Laboratory of Digital Stomatology, National Medical Products Administration, Key Laboratory for Dental Materials, Research Center of Engineering and Technology for Digital Dentistry, Ministry of Health, Beijing, 100081, ChinaThe oral and maxillofacial regions have complex anatomical structures and different tissue types, which have vital health and aesthetic functions. Biodegradable metals (BMs) is a promising bioactive materials to treat oral and maxillofacial diseases. This review summarizes the research status and future research directions of BMs for oral and maxillofacial applications. Mg-based BMs and Zn-based BMs for bone fracture fixation systems, and guided bone regeneration (GBR) membranes, are discussed in detail. Zn-based BMs with a moderate degradation rate and superior mechanical properties for GBR membranes show great potential for clinical translation. Fe-based BMs have a relatively low degradation rate and insoluble degradation products, which greatly limit their application and clinical translation. Furthermore, we proposed potential future research directions for BMs in the oral and maxillofacial regions, including 3D printed BM bone scaffolds, surface modification for BMs GBR membranes, and BMs containing hydrogels for cartilage regeneration, soft tissue regeneration, and nerve regeneration. Taken together, the progress made in the development of BMs in oral and maxillofacial regions has laid a foundation for further clinical translation.http://www.sciencedirect.com/science/article/pii/S2452199X21000153Biodegradable metalsOral and maxillofacial regionBone fractureBone fixationBone defectGuided bone regeneration |