Amelioration of Inflammatory Cytokines Mix Stimulation: A Pretreatment of CD137 Signaling Study on VSMC

Amelioration of Inflammatory Cytokines Mix Stimulation: A Pretreatment of CD137 Signaling Study on VSMC

Previous studies showed little CD137 expressed in normal vascular smooth muscle cells (VSMCs) and it is important to find a valid way to elevate it before studying its function. The level of CD137 was detected by RT-PCR, western blot, and flow cytometry, respectively. CD137 signaling activation was...

Full description

Bibliographic Details
Main Authors:	Wei Zhong, Bo Li, Xiao Yang Li, Zhong Qun Wang, Chen Shao, Cui Ping Wang, Rui Chen, Jin Chuan Yan
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2017/1382805

Similar Items

Activation of CD137 Signaling Enhances Vascular Calcification through c-Jun N-Terminal Kinase-Dependent Disruption of Autophagic Flux
by: Rui Chen, et al.
Published: (2018-01-01)

NOD2 Agonist Promotes the Production of Inflammatory Cytokines in VSMC in Synergy with TLR2 and TLR4 Agonists
by: Jinghua Sun, et al.
Published: (2012-01-01)

Contributions of Costimulatory Molecule CD137 in Endothelial Cells
by: Wei Yuan, et al.
Published: (2021-06-01)

CD137L-DCs, Potent Immune-Stimulators—History, Characteristics, and Perspectives
by: Qun Zeng, et al.
Published: (2019-10-01)

Luteolin Inhibits Angiotensin II-Stimulated VSMC Proliferation and Migration through Downregulation of Akt Phosphorylation
by: Tongda Xu, et al.
Published: (2015-01-01)

Liensinine Prevents Vascular Inflammation by Attenuating Inflammatory Mediators and Modulating VSMC Function
by: Moon Young Jun, et al.
Published: (2021-01-01)

Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axis
by: Shengchao Zhang, et al.
Published: (2021-01-01)

Soluble CD137 Ameliorates Acute Type 1 Diabetes by Inducing T Cell Anergy
by: Arata Itoh, et al.
Published: (2019-11-01)

Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis
by: Khang Luu, et al.
Published: (2021-02-01)

CD137-CD137L interaction regulates atherosclerosis via cyclophilin A in apolipoprotein E-deficient mice.
by: Yuefeng Li, et al.
Published: (2014-01-01)

Loss of FoxO3a prevents aortic aneurysm formation through maintenance of VSMC homeostasis
by: Weiling Lu, et al.
Published: (2021-04-01)

vSMC: Parallel Sequential Monte Carlo in C++
by: Yan Zhou
Published: (2015-01-01)

Baicalin ameliorates chronic mild stress-induced depression-like behaviors in mice and attenuates inflammatory cytokines and oxidative stress
by: Juying Zhong, et al.

The changes of the peripheral CD4+ lymphocytes and inflammatory cytokines in Patients with COVID-19.
by: Hua-Bao Sun, et al.
Published: (2020-01-01)

The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity
by: Beom K. Choi, et al.
Published: (2020-12-01)

Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
by: Bo Li, et al.
Published: (2020-01-01)

PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2.
by: Yi Zhou, et al.
Published: (2016-01-01)

Clinical implications of elevated serum soluble CD137 levels in patients with acute coronary syndrome
by: Jinchuan Yan, et al.
Published: (2013-01-01)

Mdivi-1, a mitochondrial fission inhibitor, reduces angiotensin-II- induced hypertension by mediating VSMC phenotypic switch
by: Yue Deng, et al.
Published: (2021-08-01)

The Progress of Investigating the CD137-CD137L Axis as a Potential Target for Systemic Lupus Erythematosus
by: Anselm Mak, et al.
Published: (2019-09-01)

Increased Akt-Driven Glycolysis Is the Basis for the Higher Potency of CD137L-DCs
by: Qun Zeng, et al.
Published: (2019-04-01)

Mesenchymal stromal cells pretreated with pro‐inflammatory cytokines promote skin wound healing through VEGFC‐mediated angiogenesis
by: Mengting Zhu, et al.
Published: (2020-10-01)

BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate
by: Annamária Nagy, et al.
Published: (2021-08-01)

Investigating the effect of Wnt proteins on VSMC behaviour and vessel remodelling during ageing
by: Monk, Bethan Alice
Published: (2016)

814 MCLA-145 (CD137xPD-L1): a potent CD137 agonist and immune checkpoint inhibitor that that does not show signs of peripheral toxicity
by: Mark Throsby, et al.
Published: (2020-11-01)

Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137
by: Li SY, et al.
Published: (2013-09-01)

Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells
by: Bo Li, et al.
Published: (2020-01-01)

Species difference of CD137 ligand signaling in human and murine monocytes.
by: Qianqiao Tang, et al.
Published: (2011-01-01)

Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells
by: Anja Trillhaase, et al.
Published: (2018-08-01)

Mitoxantrone suppresses vascular smooth muscle cell (VSMC) proliferation and balloon injury-induced neointima formation: An in vitro and in vivo study
by: Yuan Teng, et al.
Published: (2017-11-01)

Identification of CD137-Expressing B Cells in Multiple Sclerosis Which Secrete IL-6 Upon Engagement by CD137 Ligand
by: Hiu Yi Wong, et al.
Published: (2020-11-01)

Ginsenoside Re inhibits PDGF-BB-induced VSMC proliferation via the eNOS/NO/cGMP pathway
by: Yang Gao, et al.
Published: (2019-07-01)

Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells
by: Sakthi Rajendran, et al.
Published: (2019-09-01)

Inhibition of lncRNA HOTTIP ameliorated myofibroblast activities and inflammatory cytokines in oral submucous fibrosis
by: Yu-Hsien Lee, et al.
Published: (2021-05-01)

CD137 expression in cancer cells: regulation and significance
by: Christophe Glorieux, et al.
Published: (2019-11-01)

An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer
by: Dinh-Toi Chu, et al.
Published: (2019-04-01)

Pipoxolan ameliorates cerebral ischemia via inhibition of neuronal apoptosis and intimal hyperplasia through attenuation of VSMC migration and modulation of matrix metalloproteinase-2/9 and Ras/MEK/ERK signaling pathways.
by: Yuh-Fung Chen, et al.
Published: (2013-01-01)

647 Evaluation of efficacy and toxicity of CD137 immunotherapy with urelumab-mIgG1 chimeric antibody in CD137 HuGEMM™
by: Daniel He, et al.
Published: (2020-11-01)

The prognostic value of pretreatment inflammatory biomarkers in primary angiosarcoma
by: Wang M, et al.
Published: (2019-08-01)

Analysis of CD137L and IL-17 Expression in Tumor Tissue as Prognostic Indicators for Gliblastoma
by: Xiangli Cui, Zhiqin Xu, Zhigang Zhao, Dali Sui, Xiaohui Ren, Qiming Huang, Jiazhen Qin, Limin Hao, Zhenguang Wang, Li Shen, Song Lin
Published: (2013-01-01)

Cannot write session to /tmp/vufind_sessions/sess_vqott47ss66bpt5e8cuhvm5o51