Aurora kinases as targets in drug-resistant neuroblastoma cells.

Aurora kinases as targets in drug-resistant neuroblastoma cells.

Aurora kinase inhibitors displayed activity in pre-clinical neuroblastoma models. Here, we studied the effects of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) and the aurora kinase inhibitor alisertib (MLN8237) that shows some specificity for aurora kinase A over aurora kinase B in a...

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Bibliographic Details
Main Authors: Martin Michaelis, Florian Selt, Florian Rothweiler, Nadine Löschmann, Benedikt Nüsse, Wilhelm G Dirks, Richard Zehner, Jindrich Cinatl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182628?pdf=render

Internet

http://europepmc.org/articles/PMC4182628?pdf=render

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