RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Abstract ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a reg...

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Bibliographic Details
Main Authors: Maria Pujantell, Eva Riveira-Muñoz, Roger Badia, Marc Castellví, Edurne Garcia-Vidal, Guillem Sirera, Teresa Puig, Cristina Ramirez, Bonaventura Clotet, José A. Esté, Ester Ballana
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13580-0

Internet

https://doi.org/10.1038/s41598-017-13580-0

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