High-density genomewide linkage analysis of exceptional human longevity identifies multiple novel loci.

Human lifespan is approximately 25% heritable, and genetic factors may be particularly important for achieving exceptional longevity. Accordingly, siblings of centenarians have a dramatically higher probability of reaching extreme old age than the general population.To map the loci conferring a surv...

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Bibliographic Details
Main Authors: Steven E Boyden, Louis M Kunkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2930849?pdf=render