A hidden gene in astroviruses encodes a viroporin

A hidden gene in astroviruses encodes a viroporin

Astroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient production and/or release of virus particles.

Bibliographic Details
Main Authors: Valeria Lulla, Andrew E. Firth
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17906-x
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spelling doaj-b52d01832d8e493da92213e3f81e0b322021-08-15T11:42:03ZengNature Publishing GroupNature Communications2041-17232020-08-0111111510.1038/s41467-020-17906-xA hidden gene in astroviruses encodes a viroporinValeria Lulla0Andrew E. Firth1Division of Virology, Department of Pathology, Addenbrooke’s Hospital, University of CambridgeDivision of Virology, Department of Pathology, Addenbrooke’s Hospital, University of CambridgeAstroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient production and/or release of virus particles.https://doi.org/10.1038/s41467-020-17906-x
collection DOAJ
language English
format Article
sources DOAJ
author Valeria Lulla
Andrew E. Firth
spellingShingle Valeria Lulla
Andrew E. Firth
A hidden gene in astroviruses encodes a viroporin
Nature Communications
author_facet Valeria Lulla
Andrew E. Firth
author_sort Valeria Lulla
title A hidden gene in astroviruses encodes a viroporin
title_short A hidden gene in astroviruses encodes a viroporin
title_full A hidden gene in astroviruses encodes a viroporin
title_fullStr A hidden gene in astroviruses encodes a viroporin
title_full_unstemmed A hidden gene in astroviruses encodes a viroporin
title_sort hidden gene in astroviruses encodes a viroporin
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-08-01
description Astroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient production and/or release of virus particles.
url https://doi.org/10.1038/s41467-020-17906-x
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AT valerialulla hiddengeneinastrovirusesencodesaviroporin
AT andrewefirth hiddengeneinastrovirusesencodesaviroporin
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