Topical Valproate Solution for Hair Growth
Valproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose relate...
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Light House Polyclinic Mangalore
2018-05-01
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doaj-b520294c7aeb4b8191816cb16d7e3e002020-11-24T22:56:13ZengLight House Polyclinic Mangalore Online Journal of Health & Allied Sciences0972-59970972-59972018-05-01171Topical Valproate Solution for Hair GrowthAnil Kakunje0Sindhu Priya ES1Ashwini Prabhu2Ravichandra Karkal3Parmod Kumar4Nitin Gupta5Rahyanath K Pookoth6Associate Professor of Psychiatry, Yenepoya Medical College, Yenepoya University, MangaloreResearch Assistant, Yenepoya Research Centre, Yenepoya University, MangaloreAssistant Professor, Yenepoya Research Centre, Yenepoya University, MangaloreAssistant Professor of Psychiatry, Yenepoya Medical College, Yenepoya University, MangaloreConsultant Psychiatrist, Dr Parmod Clinic, ChandigarhProfessor, Dept of Psychiatry, Government Medical College, ChandigarhJunior Research Fellow, Yenepoya Research Centre, Yenepoya University, MangaloreValproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose related. A large number of drugs may interfere with the hair cycle and produce hair loss. We have only a few drugs like Minoxidil, Finasteride used for hair regeneration and both have its own side effects and limitations. In contrast to oral ingestions of valproate causing hair loss, early experiments with topical Valproic acid cream showed hair regeneration. Valproic acid cream is currently unavailable in the market, alternatively, we do have valproate and divalproex solutions available in various strengths which have a potential to be used topically for hair regeneration. The side effects and cost of topical valproate solution could be much less than the available options in the market. Valproate solution topically has the potential to be used for hair growth.https://www.ojhas.org/issue65/2018-1-14.htmlValproatehairregenerationtopical solution |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anil Kakunje Sindhu Priya ES Ashwini Prabhu Ravichandra Karkal Parmod Kumar Nitin Gupta Rahyanath K Pookoth |
spellingShingle |
Anil Kakunje Sindhu Priya ES Ashwini Prabhu Ravichandra Karkal Parmod Kumar Nitin Gupta Rahyanath K Pookoth Topical Valproate Solution for Hair Growth Online Journal of Health & Allied Sciences Valproate hair regeneration topical solution |
author_facet |
Anil Kakunje Sindhu Priya ES Ashwini Prabhu Ravichandra Karkal Parmod Kumar Nitin Gupta Rahyanath K Pookoth |
author_sort |
Anil Kakunje |
title |
Topical Valproate Solution for Hair Growth |
title_short |
Topical Valproate Solution for Hair Growth |
title_full |
Topical Valproate Solution for Hair Growth |
title_fullStr |
Topical Valproate Solution for Hair Growth |
title_full_unstemmed |
Topical Valproate Solution for Hair Growth |
title_sort |
topical valproate solution for hair growth |
publisher |
Light House Polyclinic Mangalore |
series |
Online Journal of Health & Allied Sciences |
issn |
0972-5997 0972-5997 |
publishDate |
2018-05-01 |
description |
Valproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose related. A large number of drugs may interfere with the hair cycle and produce hair loss. We have only a few drugs like Minoxidil, Finasteride used for hair regeneration and both have its own side effects and limitations. In contrast to oral ingestions of valproate causing hair loss, early experiments with topical Valproic acid cream showed hair regeneration. Valproic acid cream is currently unavailable in the market, alternatively, we do have valproate and divalproex solutions available in various strengths which have a potential to be used topically for hair regeneration. The side effects and cost of topical valproate solution could be much less than the available options in the market. Valproate solution topically has the potential to be used for hair growth. |
topic |
Valproate hair regeneration topical solution |
url |
https://www.ojhas.org/issue65/2018-1-14.html |
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