Topical Valproate Solution for Hair Growth

Valproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose relate...

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Main Authors: Anil Kakunje, Sindhu Priya ES, Ashwini Prabhu, Ravichandra Karkal, Parmod Kumar, Nitin Gupta, Rahyanath K Pookoth
Format: Article
Language:English
Published: Light House Polyclinic Mangalore 2018-05-01
Series:Online Journal of Health & Allied Sciences
Subjects:
Online Access:https://www.ojhas.org/issue65/2018-1-14.html
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spelling doaj-b520294c7aeb4b8191816cb16d7e3e002020-11-24T22:56:13ZengLight House Polyclinic Mangalore Online Journal of Health & Allied Sciences0972-59970972-59972018-05-01171Topical Valproate Solution for Hair GrowthAnil Kakunje0Sindhu Priya ES1Ashwini Prabhu2Ravichandra Karkal3Parmod Kumar4Nitin Gupta5Rahyanath K Pookoth6Associate Professor of Psychiatry, Yenepoya Medical College, Yenepoya University, MangaloreResearch Assistant, Yenepoya Research Centre, Yenepoya University, MangaloreAssistant Professor, Yenepoya Research Centre, Yenepoya University, MangaloreAssistant Professor of Psychiatry, Yenepoya Medical College, Yenepoya University, MangaloreConsultant Psychiatrist, Dr Parmod Clinic, ChandigarhProfessor, Dept of Psychiatry, Government Medical College, ChandigarhJunior Research Fellow, Yenepoya Research Centre, Yenepoya University, MangaloreValproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose related. A large number of drugs may interfere with the hair cycle and produce hair loss. We have only a few drugs like Minoxidil, Finasteride used for hair regeneration and both have its own side effects and limitations. In contrast to oral ingestions of valproate causing hair loss, early experiments with topical Valproic acid cream showed hair regeneration. Valproic acid cream is currently unavailable in the market, alternatively, we do have valproate and divalproex solutions available in various strengths which have a potential to be used topically for hair regeneration. The side effects and cost of topical valproate solution could be much less than the available options in the market. Valproate solution topically has the potential to be used for hair growth.https://www.ojhas.org/issue65/2018-1-14.htmlValproatehairregenerationtopical solution
collection DOAJ
language English
format Article
sources DOAJ
author Anil Kakunje
Sindhu Priya ES
Ashwini Prabhu
Ravichandra Karkal
Parmod Kumar
Nitin Gupta
Rahyanath K Pookoth
spellingShingle Anil Kakunje
Sindhu Priya ES
Ashwini Prabhu
Ravichandra Karkal
Parmod Kumar
Nitin Gupta
Rahyanath K Pookoth
Topical Valproate Solution for Hair Growth
Online Journal of Health & Allied Sciences
Valproate
hair
regeneration
topical solution
author_facet Anil Kakunje
Sindhu Priya ES
Ashwini Prabhu
Ravichandra Karkal
Parmod Kumar
Nitin Gupta
Rahyanath K Pookoth
author_sort Anil Kakunje
title Topical Valproate Solution for Hair Growth
title_short Topical Valproate Solution for Hair Growth
title_full Topical Valproate Solution for Hair Growth
title_fullStr Topical Valproate Solution for Hair Growth
title_full_unstemmed Topical Valproate Solution for Hair Growth
title_sort topical valproate solution for hair growth
publisher Light House Polyclinic Mangalore
series Online Journal of Health & Allied Sciences
issn 0972-5997
0972-5997
publishDate 2018-05-01
description Valproate is used regularly in the treatment of various seizure disorders, bipolar disorder, migraine prophylaxis and off label in many other conditions. Alopecia or hair loss is cosmetic side effect of oral valproate administration. Hair loss with valproate is diffused, non-scarring and dose related. A large number of drugs may interfere with the hair cycle and produce hair loss. We have only a few drugs like Minoxidil, Finasteride used for hair regeneration and both have its own side effects and limitations. In contrast to oral ingestions of valproate causing hair loss, early experiments with topical Valproic acid cream showed hair regeneration. Valproic acid cream is currently unavailable in the market, alternatively, we do have valproate and divalproex solutions available in various strengths which have a potential to be used topically for hair regeneration. The side effects and cost of topical valproate solution could be much less than the available options in the market. Valproate solution topically has the potential to be used for hair growth.
topic Valproate
hair
regeneration
topical solution
url https://www.ojhas.org/issue65/2018-1-14.html
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