Functional and in silico Characterization of Neutralizing Interactions Between Antibodies and the Foot-and-Mouth Disease Virus Immunodominant Antigenic Site

Functional and in silico Characterization of Neutralizing Interactions Between Antibodies and the Foot-and-Mouth Disease Virus Immunodominant Antigenic Site

Molecular knowledge of virus–antibody interactions is essential for the development of better vaccines and for a timely assessment of the spread and severity of epidemics. For foot-and-mouth disease virus (FMDV) research, in particular, computational methods for antigen–antibody (Ag–Ab) interaction,...

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Bibliographic Details
Main Authors: Ruben Marrero Diaz de Villegas, Cristina Seki, Nora M. Mattion, Guido A. König
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Veterinary Science
Subjects:
FMDV
neutralizing antibody
peptide ELISA
functional epitope
structure modeling
docking
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.554383/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.554383/full

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