Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus

Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus

Traumatic brain injury (TBI) due to blast from improvised explosive devices has been a leading cause of morbidity and mortality in recent conflicts in Iraq and Afghanistan. However, the mechanisms of primary blast-induced TBI are not well understood. The Akt signal transduction pathway has been impl...

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Bibliographic Details
Main Authors: Yushan Wang, Thomas W. Sawyer, Yiu Chung Tse, Changyang Fan, Grant Hennes, Julia Barnes, Tyson Josey, Tracy Weiss, Peggy Nelson, Tak Pan Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neurology
Subjects:
traumatic brain injury
Akt
primary blast
N-methyl-d-aspartate receptor
neurotrauma
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00413/full

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