SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL

SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL

This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1- yl)methyl) phenol - the Mannic...

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Main Authors: AYOWOLE O. AYENI, GARETH M. WATKINS 1
Format: Article
Language:English
Published: Alma Mater Publishing House "Vasile Alecsandri" University of Bacau 2020-12-01
Series:Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry
Subjects:
aminomethylation
monobase
oxidation
piperidine
quinone
Online Access:http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186
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spelling doaj-b5084fa2fd094148ac74882b97a8efb42021-02-18T10:33:37ZengAlma Mater Publishing House "Vasile Alecsandri" University of BacauScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry1582-540X1582-540X2020-12-01214453462SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOLAYOWOLE O. AYENI0GARETH M. WATKINS 111. Rhodes University, Department of Chemistry, Grahamstown 6139, South Africa 2. Obafemi Awolowo University, Department of Chemistry, Ile-Ife 220005, Nigeria1. Rhodes University, Department of Chemistry, Grahamstown 6139, South Africa This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1- yl)methyl) phenol - the Mannich base and its synthesized metal complexes were characterized by various spectroscopic techniques including NMR, IR, and UV-Vis spectroscopy. Turnover rates obtained from the Cu(II) and Fe(III) complexes ranged between 6.02 - 22.72 h-1 with the thiocyanate mode in the Fe(III) complex leading to increased catecholase activity. http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186aminomethylationmonobaseoxidationpiperidinequinone
collection DOAJ
language English
format Article
sources DOAJ
author AYOWOLE O. AYENI
GARETH M. WATKINS 1
spellingShingle AYOWOLE O. AYENI
GARETH M. WATKINS 1
SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry
aminomethylation
monobase
oxidation
piperidine
quinone
author_facet AYOWOLE O. AYENI
GARETH M. WATKINS 1
author_sort AYOWOLE O. AYENI
title SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
title_short SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
title_full SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
title_fullStr SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
title_full_unstemmed SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
title_sort synthesis and catecholase activity of cu(ii) and fe(iii) complexes of 4-methyl-2-((piperidin-1-yl)methyl)phenol
publisher Alma Mater Publishing House "Vasile Alecsandri" University of Bacau
series Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry
issn 1582-540X
1582-540X
publishDate 2020-12-01
description This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1- yl)methyl) phenol - the Mannich base and its synthesized metal complexes were characterized by various spectroscopic techniques including NMR, IR, and UV-Vis spectroscopy. Turnover rates obtained from the Cu(II) and Fe(III) complexes ranged between 6.02 - 22.72 h-1 with the thiocyanate mode in the Fe(III) complex leading to increased catecholase activity.
topic aminomethylation
monobase
oxidation
piperidine
quinone
url http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186
work_keys_str_mv AT ayowoleoayeni synthesisandcatecholaseactivityofcuiiandfeiiicomplexesof4methyl2piperidin1ylmethylphenol
AT garethmwatkins1 synthesisandcatecholaseactivityofcuiiandfeiiicomplexesof4methyl2piperidin1ylmethylphenol
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