Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site

Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site

Abstract Background A wide variety of DNA lesions interfere with replication and transcription, leading to mutations and cell death. DNA repair mechanisms act upon these DNA lesions present in the genomic DNA. To investigate a DNA repair mechanism elaborately, an in vitro DNA repair substrate contai...

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Bibliographic Details
Main Authors: Mika Yukutake, Mika Hayashida, Narumi Shioi Aoki, Isao Kuraoka
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Genes and Environment
Subjects:
DNA lesion
In vitro DNA repair substrate
In vitro assay
Online Access:http://link.springer.com/article/10.1186/s41021-018-0112-5

Internet

http://link.springer.com/article/10.1186/s41021-018-0112-5

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