Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis

Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis

Differences between the solid-state 13C CP-MAS NMR spectra of holemic samples of the two enantiomers of 2,2′-dihydroxy-1,1′-binaphthyl (binol) were not sufficiently emphatic to reliably distinguish them, though they are readily distinguishable from the spectrum of the bimate of the compound crystall...

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Main Author: Karel D. Klika
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2013/970654
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spelling doaj-b5007d8a6b324cf99bf7d265257521c82020-11-25T00:13:51ZengHindawi LimitedJournal of Spectroscopy2314-49202314-49392013-01-01201310.1155/2013/970654970654Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral AnalysisKarel D. Klika0Department of Chemistry, University of Turku, Vatselankatu 2, 20014 Turku, FinlandDifferences between the solid-state 13C CP-MAS NMR spectra of holemic samples of the two enantiomers of 2,2′-dihydroxy-1,1′-binaphthyl (binol) were not sufficiently emphatic to reliably distinguish them, though they are readily distinguishable from the spectrum of the bimate of the compound crystallized from an equimatic sample. Inducing an additional chiral environment by cocondensation with sucrose as a chiral selector (CS) provided a method to yield differential spectra for the two enantiomers and thus effect enantiodifferentiation by way of solid-state NMR using weak interactions from a CS.http://dx.doi.org/10.1155/2013/970654
collection DOAJ
language English
format Article
sources DOAJ
author Karel D. Klika
spellingShingle Karel D. Klika
Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
Journal of Spectroscopy
author_facet Karel D. Klika
author_sort Karel D. Klika
title Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
title_short Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
title_full Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
title_fullStr Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
title_full_unstemmed Chiral Solid Solutions for the NMR Analysis of Enantiomers: A Potential New Approach to Chiral Analysis
title_sort chiral solid solutions for the nmr analysis of enantiomers: a potential new approach to chiral analysis
publisher Hindawi Limited
series Journal of Spectroscopy
issn 2314-4920
2314-4939
publishDate 2013-01-01
description Differences between the solid-state 13C CP-MAS NMR spectra of holemic samples of the two enantiomers of 2,2′-dihydroxy-1,1′-binaphthyl (binol) were not sufficiently emphatic to reliably distinguish them, though they are readily distinguishable from the spectrum of the bimate of the compound crystallized from an equimatic sample. Inducing an additional chiral environment by cocondensation with sucrose as a chiral selector (CS) provided a method to yield differential spectra for the two enantiomers and thus effect enantiodifferentiation by way of solid-state NMR using weak interactions from a CS.
url http://dx.doi.org/10.1155/2013/970654
work_keys_str_mv AT kareldklika chiralsolidsolutionsforthenmranalysisofenantiomersapotentialnewapproachtochiralanalysis
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