Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease

Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease

The human gut is colonized by a large number of microorganisms (∼1013 bacteria) that support various physiologic functions. A perturbation in the healthy gut microbiome might lead to the development of inflammatory diseases, such as multiple sclerosis (MS). Therefore, gut commensals might provide pr...

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Bibliographic Details
Main Authors: Ashutosh Mangalam, Shailesh K. Shahi, David Luckey, Melissa Karau, Eric Marietta, Ningling Luo, Rok Seon Choung, Josephine Ju, Ramakrishna Sompallae, Katherine Gibson-Corley, Robin Patel, Moses Rodriguez, Chella David, Veena Taneja, Joseph Murray
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
multiple sclerosis
human commensal
gut microbiome
experimental autoimmune encephalomyelitis
EAE
Prevotella histicola
immunomodulation
inflammation
demyelination
regulatory T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471730997X

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http://www.sciencedirect.com/science/article/pii/S221112471730997X

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