Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK

Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK

BackgroundSelenoprotein P (SEPP1) and fetuin-A, both circulating liver-derived glycoproteins, are novel biomarkers for insulin resistance and nonalcoholic fatty liver disease. However, the effect of exendin-4 (Ex-4), a glucagon-like peptide-1 receptor agonist, on the expression of hepatokines, SEPP1...

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Bibliographic Details
Main Authors: Jinmi Lee, Seok-Woo Hong, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee
Format: Article
Language:English
Published: Academya Publishing Co. 2015-06-01
Series:Endocrinology and Metabolism
Subjects:
Exendin-4
Palmitic acid
Endoplasmic reticulum stress
AMP-activated protein kinases
Selenoprotein P
Fetuin-A
Hepatokine
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-177.pdf

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