Dietary GABA and its combination with vigabatrin mimic calorie restriction and induce antiobesity-like effects in lean mice

Dietary GABA and its combination with vigabatrin mimic calorie restriction and induce antiobesity-like effects in lean mice

The anti-obesity and anti-diabetic effects of γ-aminobutyric acid (GABA) are mainly expressed via glucose and insulin regulation in mice. It is unknown whether dietary GABA exerts anti-obesity effects via other pathways. Herein, we report that a high dietary GABA intake (5%) significantly suppressed...

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Bibliographic Details
Main Authors: Kanako Sato, Takumi Komaru, Takeshi Arima, Chanakarn Jardson, Noriyuki Yanaka, Thanutchaporn Kumrungsee
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Functional Foods
Subjects:
GABA
β-aminoisobutyric acid
Vigabatrin
GABA transaminase
Anti-obesity
Brain
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000165

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