VEGFR2 Promotes Metastasis and PD-L2 Expression of Human Osteosarcoma Cells by Activating the STAT3 and RhoA-ROCK-LIMK2 Pathways

VEGFR2 Promotes Metastasis and PD-L2 Expression of Human Osteosarcoma Cells by Activating the STAT3 and RhoA-ROCK-LIMK2 Pathways

The survival rate of osteosarcoma, the most prevalent primary bone tumor, has not been effectively improved in the last 30 years. Hence, new treatments and drugs are urgently needed. Antiangiogenic therapy and immunotherapy have good antitumor effects in many kinds of tumors. It is hypothesized that...

Full description

Bibliographic Details
Main Authors: Bingxin Zheng, Chuanli Zhou, Guojian Qu, Chongmin Ren, Peng Yan, Wei Guo, Bin Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
VEGFR2
PD-L2
STAT3
metastasis
osteosarcoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.543562/full

Similar Items

Similar Items