Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.

Despite advances in radical surgery and chemotherapy delivery, ovarian cancer is the most lethal gynecologic malignancy. Standard therapy includes treatment with platinum-based combination chemotherapies yet there is no biomarker model to predict their responses to these agents. We here have develop...

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Bibliographic Details
Main Authors: J Stuart Ferriss, Youngchul Kim, Linda Duska, Michael Birrer, Douglas A Levine, Christopher Moskaluk, Dan Theodorescu, Jae K Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3277593?pdf=render