Phenotypic resistance and the dynamics of bacterial escape from phage control.
The canonical view of phage - bacterial interactions in dense, liquid cultures is that the phage will eliminate most of the sensitive cells; genetic resistance will then ascend to restore high bacterial densities. Yet there are various mechanisms by which bacteria may remain sensitive to phages but...
Main Authors: | James J Bull, Christina Skovgaard Vegge, Matthew Schmerer, Waqas Nasir Chaudhry, Bruce R Levin |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3990542?pdf=render |
Similar Items
-
Synergy as a rationale for phage therapy using phage cocktails
by: Matthew Schmerer, et al.
Published: (2014-09-01) -
Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms.
by: Waqas Nasir Chaudhry, et al.
Published: (2017-01-01) -
The phenotype-fitness map in experimental evolution of phages.
by: James J Bull, et al.
Published: (2011-01-01) -
Phage “delay” towards enhancing bacterial escape from biofilms: a more comprehensive way of viewing resistance to bacteriophages
by: Stephen T. Abedon
Published: (2017-03-01) -
Phage-Bacterial Dynamics with Spatial Structure: Self Organization around Phage Sinks Can Promote Increased Cell Densities
by: James J. Bull, et al.
Published: (2018-01-01)