Phenotypic resistance and the dynamics of bacterial escape from phage control.

The canonical view of phage - bacterial interactions in dense, liquid cultures is that the phage will eliminate most of the sensitive cells; genetic resistance will then ascend to restore high bacterial densities. Yet there are various mechanisms by which bacteria may remain sensitive to phages but...

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Bibliographic Details
Main Authors: James J Bull, Christina Skovgaard Vegge, Matthew Schmerer, Waqas Nasir Chaudhry, Bruce R Levin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990542?pdf=render