“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”

The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruse...

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Main Authors: Rishabh Agrahari, Sonali Mohanty, Kanchan Vishwakarma, Suraja Kumar Nayak, Deviprasad Samantaray, Swati Mohapatra
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-01-01
Series:Sensors International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666351120300735
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spelling doaj-b4e1a2adc4254ff595779dd2109c7fe82021-04-02T16:37:13ZengKeAi Communications Co., Ltd.Sensors International2666-35112021-01-012100073“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”Rishabh Agrahari0Sonali Mohanty1Kanchan Vishwakarma2Suraja Kumar Nayak3Deviprasad Samantaray4Swati Mohapatra5Amity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, IndiaDepartment of Microbiology, CBSH, OUAT, Bhubaneswar, Odisha, IndiaAmity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, IndiaDepartment of Biotechnology, CET, Bhubaneswar, Odisha, IndiaDepartment of Microbiology, CBSH, OUAT, Bhubaneswar, Odisha, IndiaAmity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, India; Corresponding author.The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruses are being reported to infect humans, however the seventh one is genetically similar to the SARS Coronavirus and termed as SARS-CoV-2. Specific crucial macromolecules such as membrane, nuclear, spike and enveloped proteins including HE esterase are present in the virus that interact with ACE2, APN, NEU-5, 9SC2 moiety of humans plays significant role in occurrence and transmission of the devastating disease. This review article summarizes the structure, histopathology, transmission of novel Coronavirus, its symptoms with preventive measures & currently prescribed drugs. Though various drugs and therapy have been administrated or implemented to restrict COVID-19, however it is imperative to develop an antidote against SARS-CoV-2 by the scientific or research community to save life.http://www.sciencedirect.com/science/article/pii/S2666351120300735SARS-CoV2PathogenesisOriginReplicationMedication
collection DOAJ
language English
format Article
sources DOAJ
author Rishabh Agrahari
Sonali Mohanty
Kanchan Vishwakarma
Suraja Kumar Nayak
Deviprasad Samantaray
Swati Mohapatra
spellingShingle Rishabh Agrahari
Sonali Mohanty
Kanchan Vishwakarma
Suraja Kumar Nayak
Deviprasad Samantaray
Swati Mohapatra
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
Sensors International
SARS-CoV2
Pathogenesis
Origin
Replication
Medication
author_facet Rishabh Agrahari
Sonali Mohanty
Kanchan Vishwakarma
Suraja Kumar Nayak
Deviprasad Samantaray
Swati Mohapatra
author_sort Rishabh Agrahari
title “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
title_short “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
title_full “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
title_fullStr “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
title_full_unstemmed “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
title_sort “update vision on covid-19: structure, immune pathogenesis, treatment and safety assessment”
publisher KeAi Communications Co., Ltd.
series Sensors International
issn 2666-3511
publishDate 2021-01-01
description The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruses are being reported to infect humans, however the seventh one is genetically similar to the SARS Coronavirus and termed as SARS-CoV-2. Specific crucial macromolecules such as membrane, nuclear, spike and enveloped proteins including HE esterase are present in the virus that interact with ACE2, APN, NEU-5, 9SC2 moiety of humans plays significant role in occurrence and transmission of the devastating disease. This review article summarizes the structure, histopathology, transmission of novel Coronavirus, its symptoms with preventive measures & currently prescribed drugs. Though various drugs and therapy have been administrated or implemented to restrict COVID-19, however it is imperative to develop an antidote against SARS-CoV-2 by the scientific or research community to save life.
topic SARS-CoV2
Pathogenesis
Origin
Replication
Medication
url http://www.sciencedirect.com/science/article/pii/S2666351120300735
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