“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”
The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruse...
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doaj-b4e1a2adc4254ff595779dd2109c7fe82021-04-02T16:37:13ZengKeAi Communications Co., Ltd.Sensors International2666-35112021-01-012100073“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment”Rishabh Agrahari0Sonali Mohanty1Kanchan Vishwakarma2Suraja Kumar Nayak3Deviprasad Samantaray4Swati Mohapatra5Amity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, IndiaDepartment of Microbiology, CBSH, OUAT, Bhubaneswar, Odisha, IndiaAmity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, IndiaDepartment of Biotechnology, CET, Bhubaneswar, Odisha, IndiaDepartment of Microbiology, CBSH, OUAT, Bhubaneswar, Odisha, IndiaAmity Institute of Microbial Technology, Amity University, Uttar-pradesh, Noida, India; Corresponding author.The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruses are being reported to infect humans, however the seventh one is genetically similar to the SARS Coronavirus and termed as SARS-CoV-2. Specific crucial macromolecules such as membrane, nuclear, spike and enveloped proteins including HE esterase are present in the virus that interact with ACE2, APN, NEU-5, 9SC2 moiety of humans plays significant role in occurrence and transmission of the devastating disease. This review article summarizes the structure, histopathology, transmission of novel Coronavirus, its symptoms with preventive measures & currently prescribed drugs. Though various drugs and therapy have been administrated or implemented to restrict COVID-19, however it is imperative to develop an antidote against SARS-CoV-2 by the scientific or research community to save life.http://www.sciencedirect.com/science/article/pii/S2666351120300735SARS-CoV2PathogenesisOriginReplicationMedication |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rishabh Agrahari Sonali Mohanty Kanchan Vishwakarma Suraja Kumar Nayak Deviprasad Samantaray Swati Mohapatra |
spellingShingle |
Rishabh Agrahari Sonali Mohanty Kanchan Vishwakarma Suraja Kumar Nayak Deviprasad Samantaray Swati Mohapatra “Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” Sensors International SARS-CoV2 Pathogenesis Origin Replication Medication |
author_facet |
Rishabh Agrahari Sonali Mohanty Kanchan Vishwakarma Suraja Kumar Nayak Deviprasad Samantaray Swati Mohapatra |
author_sort |
Rishabh Agrahari |
title |
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” |
title_short |
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” |
title_full |
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” |
title_fullStr |
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” |
title_full_unstemmed |
“Update vision on COVID-19: Structure, immune pathogenesis, treatment and safety assessment” |
title_sort |
“update vision on covid-19: structure, immune pathogenesis, treatment and safety assessment” |
publisher |
KeAi Communications Co., Ltd. |
series |
Sensors International |
issn |
2666-3511 |
publishDate |
2021-01-01 |
description |
The on-going SARS-CoV-2 causing COVID-19 discovered in December 2019, is responsible for a global pandemic. The virus belongs to the group of enveloped viruses containing linear, non-segmented, single stranded, positive sense strand RNA as genetic material. Already six different strains Coronaviruses are being reported to infect humans, however the seventh one is genetically similar to the SARS Coronavirus and termed as SARS-CoV-2. Specific crucial macromolecules such as membrane, nuclear, spike and enveloped proteins including HE esterase are present in the virus that interact with ACE2, APN, NEU-5, 9SC2 moiety of humans plays significant role in occurrence and transmission of the devastating disease. This review article summarizes the structure, histopathology, transmission of novel Coronavirus, its symptoms with preventive measures & currently prescribed drugs. Though various drugs and therapy have been administrated or implemented to restrict COVID-19, however it is imperative to develop an antidote against SARS-CoV-2 by the scientific or research community to save life. |
topic |
SARS-CoV2 Pathogenesis Origin Replication Medication |
url |
http://www.sciencedirect.com/science/article/pii/S2666351120300735 |
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