Identification of active and inactive agonists/antagonists of estrogen receptor based on Tox21 10K compound library: Binomial analysis and structure alert
Endocrine disrupting chemicals can mimic, block, or interfere with hormones in organisms and subsequently affect their development and reproduction, which has raised significant public concern over the past several decades. To investigate (quantitative) structure–activity relationship, 8280 compound...
Main Authors: | Jia Wang, Ying Huang, Shuo Wang, Yi Yang, Jia He, Chao Li, Yuan H. Zhao, Christopher J. Martyniuk |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
|
Series: | Ecotoxicology and Environmental Safety |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651321002256 |
Similar Items
-
A Novel Phytoestrogen that Acts as an Agonist for Human Estrogen Receptors.
by: Pearce, Virginia
Published: (2001) -
Repurposing Estrogen Receptor Antagonists for the Treatment of Infectious Disease
by: Marhiah C. Montoya, et al.
Published: (2018-12-01) -
PROSPECTS OF Toll-LIKE RECEPTOR AGONISTS AND ANTAGONISTS FOR PREVENTION AND TREATMENT OF VIRAL INFECTIONS
by: A. A. Nikonova, et al.
Published: (2019-07-01) -
PROSPECTS OF TOLL-LIKE RECEPTOR AGONISTS AND ANTAGONISTS FOR PREVENTION AND TREATMENT OF VIRAL INFECTIONS
by: Alexandra Alexandrovna Nikonova, et al.
Published: (2019-03-01) -
Phytochemicals and Estrogen-Receptor Agonists from the Aerial Parts of Liriope platyphylla
by: Yu-Chi Tsai, et al.
Published: (2015-04-01)