Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions.

Disruption of certain genes can reveal cryptic genetic variants that do not typically show phenotypic effects. Because this phenomenon, which is referred to as 'phenotypic capacitance', is a potential source of trait variation and disease risk, it is important to understand how it arises a...

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Bibliographic Details
Main Authors: Matthew B Taylor, Ian M Ehrenreich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4618523?pdf=render