Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment

Introduction. The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. Materials and Methods. A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18–65 years a...

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Main Authors: Monica del-Rio-Vellosillo, Jose Javier Garcia-Medina, Antonio Abengochea-Cotaina, Maria Dolores Pinazo-Duran, Manuel Barbera-Alacreu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/349034
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spelling doaj-b4c126e2a38d4b68a2fee9f3bb2114f72020-11-24T23:02:34ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/349034349034Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological AssessmentMonica del-Rio-Vellosillo0Jose Javier Garcia-Medina1Antonio Abengochea-Cotaina2Maria Dolores Pinazo-Duran3Manuel Barbera-Alacreu4Department of Anesthesia, University Hospital Virgen de la Arrixaca, Ctra. Madrid-Cartagena, s/n, El Palmar, 30120 Murcia, SpainDepartment of Ophthalmology and Optometry, School of Medicine, University of Murcia, Avenida Intendente Jorge Palacios 1, 30003 Murcia, SpainDepartment of Anesthesia, University Hospital La Fe, Bulevar del Sur, 46026 Valencia, SpainDepartment of Ophthalmology, University School of Medicine, University of Valencia, Avenida Blasco Ibáñez 15-17, 46010 Valencia, SpainDepartment of Anesthesia, University Hospital La Fe, Bulevar del Sur, 46026 Valencia, SpainIntroduction. The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. Materials and Methods. A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18–65 years awaiting knee arthroscopy under spinal anesthesia. Patients received 12.5 mg of isobaric bupivacaine or levobupivacaine. Several features were recorded. Results. No significant intergroup differences were observed for ASA classification, time to micturate, demographic data, surgery duration, and patient/surgeon satisfaction. Similar hemodynamic parameters and sensory/motor blockade duration were found for both groups. There were no neuroophthalmological effects in either group. Sensory (P=0.018) and motor blockade onset (P=0.003) was faster in the bupivacaine group. T6 (T2–T12) and T3 (T2–T12) were the highest sensory block levels for the levobupivacaine and bupivacaine groups, respectively (P=0.008). It took less time to regain maximum motor blockade in the bupivacaine group (P=0.014), and the levobupivacaine group required use of analgesia earlier (P=0.025). Conclusions. Isobaric bupivacaine and levobupivacaine are analogous and well-tolerated anesthetics for knee arthroscopy. However, for bupivacaine, sensory and motor blockade onset was faster, and greater sensory blockade with a longer postoperative painless period was achieved.http://dx.doi.org/10.1155/2014/349034
collection DOAJ
language English
format Article
sources DOAJ
author Monica del-Rio-Vellosillo
Jose Javier Garcia-Medina
Antonio Abengochea-Cotaina
Maria Dolores Pinazo-Duran
Manuel Barbera-Alacreu
spellingShingle Monica del-Rio-Vellosillo
Jose Javier Garcia-Medina
Antonio Abengochea-Cotaina
Maria Dolores Pinazo-Duran
Manuel Barbera-Alacreu
Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
BioMed Research International
author_facet Monica del-Rio-Vellosillo
Jose Javier Garcia-Medina
Antonio Abengochea-Cotaina
Maria Dolores Pinazo-Duran
Manuel Barbera-Alacreu
author_sort Monica del-Rio-Vellosillo
title Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
title_short Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
title_full Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
title_fullStr Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
title_full_unstemmed Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment
title_sort spinal anesthesia for knee arthroscopy using isobaric bupivacaine and levobupivacaine: anesthetic and neuroophthalmological assessment
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2014-01-01
description Introduction. The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. Materials and Methods. A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18–65 years awaiting knee arthroscopy under spinal anesthesia. Patients received 12.5 mg of isobaric bupivacaine or levobupivacaine. Several features were recorded. Results. No significant intergroup differences were observed for ASA classification, time to micturate, demographic data, surgery duration, and patient/surgeon satisfaction. Similar hemodynamic parameters and sensory/motor blockade duration were found for both groups. There were no neuroophthalmological effects in either group. Sensory (P=0.018) and motor blockade onset (P=0.003) was faster in the bupivacaine group. T6 (T2–T12) and T3 (T2–T12) were the highest sensory block levels for the levobupivacaine and bupivacaine groups, respectively (P=0.008). It took less time to regain maximum motor blockade in the bupivacaine group (P=0.014), and the levobupivacaine group required use of analgesia earlier (P=0.025). Conclusions. Isobaric bupivacaine and levobupivacaine are analogous and well-tolerated anesthetics for knee arthroscopy. However, for bupivacaine, sensory and motor blockade onset was faster, and greater sensory blockade with a longer postoperative painless period was achieved.
url http://dx.doi.org/10.1155/2014/349034
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