Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics

Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics

An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major contributor to TBI-induced brain damage. However, much remains unknown regarding the induction and regulation of the inflammatory response to TBI...

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Bibliographic Details
Main Authors: Mouna eLagraoui, Joseph R. Latoche, Natalia G. Cartwright, Gauthaman eSukumar, Clifton L. Dalgard, Brian C. Schaefer
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Neurology
Subjects:
Astrocytes
Craniotomy
Cytokines
Genomics
Inflammation
Microglia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00155/full

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