Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds

Chronic heart failure (CHF) affects over 26 million of people worldwide, and its incidence is increasing by 2% annually. Despite the significant burden that CHF poses and despite the ubiquity of sensors in our lives, methods for automatically detecting CHF are surprisingly scarce, even in the resear...

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Main Authors: Martin Gjoreski, Anton Gradisek, Borut Budna, Matjaz Gams, Gregor Poglajen
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
PCG
Online Access:https://ieeexplore.ieee.org/document/8967080/
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spelling doaj-b4aa6b8a2e664ff2bcb76c4421335d282021-03-30T01:14:07ZengIEEEIEEE Access2169-35362020-01-018203132032410.1109/ACCESS.2020.29689008967080Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart SoundsMartin Gjoreski0https://orcid.org/0000-0002-1220-7418Anton Gradisek1https://orcid.org/0000-0001-6480-9587Borut Budna2https://orcid.org/0000-0002-4846-2816Matjaz Gams3https://orcid.org/0000-0002-5747-0711Gregor Poglajen4https://orcid.org/0000-0003-1777-8807Jozef Stefan Institute, Ljubljana, SloveniaJozef Stefan Institute, Ljubljana, SloveniaJozef Stefan Institute, Ljubljana, SloveniaJozef Stefan Institute, Ljubljana, SloveniaDepartment of Cardiology, Advanced Heart Failure and Transplantation Program, UMC Ljubljana, Ljubljana, SloveniaChronic heart failure (CHF) affects over 26 million of people worldwide, and its incidence is increasing by 2% annually. Despite the significant burden that CHF poses and despite the ubiquity of sensors in our lives, methods for automatically detecting CHF are surprisingly scarce, even in the research community. We present a method for CHF detection based on heart sounds. The method combines classic Machine-Learning (ML) and end-to-end Deep Learning (DL). The classic ML learns from expert features, and the DL learns from a spectro-temporal representation of the signal. The method was evaluated on recordings from 947 subjects from six publicly available datasets and one CHF dataset that was collected for this study. Using the same evaluation method as a recent PhysoNet challenge, the proposed method achieved a score of 89.3, which is 9.1 higher than the challenge's baseline method. The method's aggregated accuracy is 92.9% (error of 7.1%); while the experimental results are not directly comparable, this error rate is relatively close to the percentage of recordings labeled as “unknown” by experts (9.7%). Finally, we identified 15 expert features that are useful for building ML models to differentiate between CHF phases (i.e., in the decompensated phase during hospitalization and in the recompensated phase) with an accuracy of 93.2%. The proposed method shows promising results both for the distinction of recordings between healthy subjects and patients and for the detection of different CHF phases. This may lead to the easier identification of new CHF patients and the development of home-based CHF monitors for avoiding hospitalizations.https://ieeexplore.ieee.org/document/8967080/Chronic heart failuredeep learningheart soundsmachine learningPCG
collection DOAJ
language English
format Article
sources DOAJ
author Martin Gjoreski
Anton Gradisek
Borut Budna
Matjaz Gams
Gregor Poglajen
spellingShingle Martin Gjoreski
Anton Gradisek
Borut Budna
Matjaz Gams
Gregor Poglajen
Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
IEEE Access
Chronic heart failure
deep learning
heart sounds
machine learning
PCG
author_facet Martin Gjoreski
Anton Gradisek
Borut Budna
Matjaz Gams
Gregor Poglajen
author_sort Martin Gjoreski
title Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
title_short Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
title_full Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
title_fullStr Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
title_full_unstemmed Machine Learning and End-to-End Deep Learning for the Detection of Chronic Heart Failure From Heart Sounds
title_sort machine learning and end-to-end deep learning for the detection of chronic heart failure from heart sounds
publisher IEEE
series IEEE Access
issn 2169-3536
publishDate 2020-01-01
description Chronic heart failure (CHF) affects over 26 million of people worldwide, and its incidence is increasing by 2% annually. Despite the significant burden that CHF poses and despite the ubiquity of sensors in our lives, methods for automatically detecting CHF are surprisingly scarce, even in the research community. We present a method for CHF detection based on heart sounds. The method combines classic Machine-Learning (ML) and end-to-end Deep Learning (DL). The classic ML learns from expert features, and the DL learns from a spectro-temporal representation of the signal. The method was evaluated on recordings from 947 subjects from six publicly available datasets and one CHF dataset that was collected for this study. Using the same evaluation method as a recent PhysoNet challenge, the proposed method achieved a score of 89.3, which is 9.1 higher than the challenge's baseline method. The method's aggregated accuracy is 92.9% (error of 7.1%); while the experimental results are not directly comparable, this error rate is relatively close to the percentage of recordings labeled as “unknown” by experts (9.7%). Finally, we identified 15 expert features that are useful for building ML models to differentiate between CHF phases (i.e., in the decompensated phase during hospitalization and in the recompensated phase) with an accuracy of 93.2%. The proposed method shows promising results both for the distinction of recordings between healthy subjects and patients and for the detection of different CHF phases. This may lead to the easier identification of new CHF patients and the development of home-based CHF monitors for avoiding hospitalizations.
topic Chronic heart failure
deep learning
heart sounds
machine learning
PCG
url https://ieeexplore.ieee.org/document/8967080/
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