Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats

Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats

Context Clinical reports showed sildenafil beneficial therapy on severe chronic obstructive pulmonary disease (COPD) with pulmonary hypertension (PH) patients. Objective The study investigated therapeutic effects of silenafil on pulmonary damage induced by cigarette smoke exposure and bacterial inha...

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Bibliographic Details
Main Authors: Zhouxin Ren, Jiansheng Li, Junling Shen, Haibin Yu, Xiaofeng Mei, Peng Zhao, Zhenya Xiao, Wanliu Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
chronic obstructive pulmonary disease
pulmonary hypertension
therapeutic effect
emphysema
apoptosis of bronchiolar epithelial cell
pathological changes
Online Access:http://dx.doi.org/10.1080/13880209.2019.1711135

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