Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells

Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells

Abstract Background Vasculogenic mimicry (VM) is characterized by the formation of tubular structure inside the tumor stroma. It has been shown that a small fraction of cancer cells, namely cancer stem cells (CSCs), could stimulate the development of vascular units in the tumor niche, leading to enh...

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Bibliographic Details
Main Authors: Sanya Haiaty, Mohammad-Reza Rashidi, Maryam Akbarzadeh, Ahad Bazmany, Mostafa Mostafazadeh, Saba Nikanfar, Zohre Zibaei, Reza Rahbarghazi, Mohammad Nouri
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Thymoquinone
Vasculogenic mimicry
Breast Cancer stem cells
Wnt3a/PI3K signaling pathways
Online Access:https://doi.org/10.1186/s12906-021-03246-w

Internet

https://doi.org/10.1186/s12906-021-03246-w

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