rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide

rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide

The title compound, C26H24FNO3, is a critical intermediate of a selective and competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG–CoA) reductase. Intermolecular N—H...O hydrogen bonding generates a chain along [give direction] that is the domina...

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Bibliographic Details
Main Authors: Feng-yan Zhou, Jian-ying Huang
Format: Article
Language:English
Published: International Union of Crystallography 2010-12-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536810046271
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spelling doaj-b49caf877be948069f1c3e330564d3652020-11-24T21:32:47ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682010-12-016612o3168o316810.1107/S1600536810046271rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamideFeng-yan ZhouJian-ying HuangThe title compound, C26H24FNO3, is a critical intermediate of a selective and competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG–CoA) reductase. Intermolecular N—H...O hydrogen bonding generates a chain along [give direction] that is the dominant interaction in the crystal packing. Intermolecular C—H...O interactions are also observed. http://scripts.iucr.org/cgi-bin/paper?S1600536810046271
collection DOAJ
language English
format Article
sources DOAJ
author Feng-yan Zhou
Jian-ying Huang
spellingShingle Feng-yan Zhou
Jian-ying Huang
rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
Acta Crystallographica Section E
author_facet Feng-yan Zhou
Jian-ying Huang
author_sort Feng-yan Zhou
title rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
title_short rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
title_full rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
title_fullStr rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
title_full_unstemmed rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
title_sort rac-2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2010-12-01
description The title compound, C26H24FNO3, is a critical intermediate of a selective and competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG–CoA) reductase. Intermolecular N—H...O hydrogen bonding generates a chain along [give direction] that is the dominant interaction in the crystal packing. Intermolecular C—H...O interactions are also observed.
url http://scripts.iucr.org/cgi-bin/paper?S1600536810046271
work_keys_str_mv AT fengyanzhou rac224fluorophenyl2oxo1phenylethyl4methyl3oxonphenylpentanamide
AT jianyinghuang rac224fluorophenyl2oxo1phenylethyl4methyl3oxonphenylpentanamide
_version_ 1725955892734590976

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