Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria

Josef YayanDepartment of Internal Medicine, Vinzentius Hospital, Landau, GermanyBackground: Patients with unstable angina or myocardial infarction are at risk of acute kidney injury, which may be aggravated by the iodine-containing contrast agent used during coronary angiography; however, the relati...

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Main Author: Yayan J
Format: Article
Language:English
Published: Dove Medical Press 2012-10-01
Series:International Journal of General Medicine
Online Access:http://www.dovepress.com/coronary-heart-disease-is-not-significantly-linked-to-acute-kidney-inj-a11234
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spelling doaj-b48d50d79e544c2c9a8bce6c6fad818c2020-11-24T23:52:37ZengDove Medical PressInternational Journal of General Medicine1178-70742012-10-012012default831838Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteriaYayan JJosef YayanDepartment of Internal Medicine, Vinzentius Hospital, Landau, GermanyBackground: Patients with unstable angina or myocardial infarction are at risk of acute kidney injury, which may be aggravated by the iodine-containing contrast agent used during coronary angiography; however, the relationship between these two conditions remains unclear.Objective: The current study investigated the relationship between acute kidney injury and coronary heart disease prior to coronary angiography.Methods: All patients were evaluated after undergoing coronary angiography in the cardiac catheterization laboratory of the Vinzentius Hospital in Landau, Germany, in 2011. The study group included patients with both acute coronary heart disease and acute kidney injury (as defined according to the classification of the Acute Kidney Injury Group); the control group included patients without acute coronary heart disease. Serum creatinine profiles were evaluated in all patients, as were a variety of demographic and health characteristics.Results: Of the 303 patients examined, 201 (66.34%) had coronary artery disease. Of these, 38 (18.91%) also had both acute kidney injury and acute coronary heart disease prior to and after coronary angiography, and of which in turn 34 (16.91%) had both acute kidney injury and acute coronary heart disease only prior to the coronary angiography. However, the occurrence of acute kidney injury was not significantly related to the presence of coronary heart disease (P = 0.95, Chi-square test).Conclusion: The results of this study indicate that acute kidney injury is not linked to acute coronary heart disease. However, physicians should be aware that many coronary heart patients may develop kidney injury while hospitalized for angiography.Keywords: acute kidney injury, acute coronary heart disease, myocardial infarction, angina pectoris, incidence, associationhttp://www.dovepress.com/coronary-heart-disease-is-not-significantly-linked-to-acute-kidney-inj-a11234
collection DOAJ
language English
format Article
sources DOAJ
author Yayan J
spellingShingle Yayan J
Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
International Journal of General Medicine
author_facet Yayan J
author_sort Yayan J
title Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
title_short Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
title_full Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
title_fullStr Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
title_full_unstemmed Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria
title_sort coronary heart disease is not significantly linked to acute kidney injury identified using acute kidney injury group criteria
publisher Dove Medical Press
series International Journal of General Medicine
issn 1178-7074
publishDate 2012-10-01
description Josef YayanDepartment of Internal Medicine, Vinzentius Hospital, Landau, GermanyBackground: Patients with unstable angina or myocardial infarction are at risk of acute kidney injury, which may be aggravated by the iodine-containing contrast agent used during coronary angiography; however, the relationship between these two conditions remains unclear.Objective: The current study investigated the relationship between acute kidney injury and coronary heart disease prior to coronary angiography.Methods: All patients were evaluated after undergoing coronary angiography in the cardiac catheterization laboratory of the Vinzentius Hospital in Landau, Germany, in 2011. The study group included patients with both acute coronary heart disease and acute kidney injury (as defined according to the classification of the Acute Kidney Injury Group); the control group included patients without acute coronary heart disease. Serum creatinine profiles were evaluated in all patients, as were a variety of demographic and health characteristics.Results: Of the 303 patients examined, 201 (66.34%) had coronary artery disease. Of these, 38 (18.91%) also had both acute kidney injury and acute coronary heart disease prior to and after coronary angiography, and of which in turn 34 (16.91%) had both acute kidney injury and acute coronary heart disease only prior to the coronary angiography. However, the occurrence of acute kidney injury was not significantly related to the presence of coronary heart disease (P = 0.95, Chi-square test).Conclusion: The results of this study indicate that acute kidney injury is not linked to acute coronary heart disease. However, physicians should be aware that many coronary heart patients may develop kidney injury while hospitalized for angiography.Keywords: acute kidney injury, acute coronary heart disease, myocardial infarction, angina pectoris, incidence, association
url http://www.dovepress.com/coronary-heart-disease-is-not-significantly-linked-to-acute-kidney-inj-a11234
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