Concise and Gram-Scale Total Synthesis of Lansiumamides A and B and Alatamide

Concise and Gram-Scale Total Synthesis of Lansiumamides A and B and Alatamide

The total synthesis of potent anti-obesity lansiumamide B was accomplished in four steps using commercially available materials. The synthetic strategy, featured with copper-catalyzed Buchwald coupling, is concise, convergent, practical and can be carried out on a one-gram scale. This approach could...

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Bibliographic Details
Main Authors: Ran Lin, Xi Lin, Qian Su, Binbin Guo, Yanqin Huang, Ming-An Ouyang, Liyan Song, Huiyou Xu
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
total synthesis
lansiumamide
alatamide
copper-catalyzed buchwald coupling
Online Access:https://www.mdpi.com/1420-3049/24/20/3764

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