LGALS3 and AXIN1 gene variants playing role in the Wnt/ β-catenin signaling pathway are associated with mucinous component and tumor size in colorectal cancer

LGALS3 and AXIN1 gene variants playing role in the Wnt/ β-catenin signaling pathway are associated with mucinous component and tumor size in colorectal cancer

The Wnt pathway alterations have been identified in colorectal and many other cancer types. It has been reported that galectin-3 (which is encoded by the LGALS3 gene) alters the signaling mechanism in the Wnt/ β-catenin pathway by binding to β-catenin in colon and other cancers. AXIN1 is mainly res...

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Bibliographic Details
Main Authors: Gurbet Korkmaz, Cem Horozoglu, Soykan Arıkan, Zeynep Gural, Esra Kaytan Sağlam, Saime Turan, Nazlı Ezgi Özkan, Ozlem Timirci Kahraman, Ezgi Nurdan Yenilmez, Yigit Düzköylü, Mehmet Baki Doğan, Umit Zeybek, Arzu Ergen, İlhan Yaylım
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2016-02-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Colorectal Cancer
LGALS3
AXIN1
ASO-PCR
PCR-RFLP
Online Access:https://bjbms.org/ojs/index.php/bjbms/article/view/721

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