Prominent Role of Histone Modifications in the Regulation of Tumor Metastasis

Prominent Role of Histone Modifications in the Regulation of Tumor Metastasis

Tumor aggressiveness and progression is highly dependent on the process of metastasis, regulated by the coordinated interplay of genetic and epigenetic mechanisms. Metastasis involves several steps of epithelial to mesenchymal transition (EMT), anoikis resistance, intra- and extravasation, and new t...

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Bibliographic Details
Main Authors: Mariam Markouli, Dimitrios Strepkos, Efthimia K. Basdra, Athanasios G. Papavassiliou, Christina Piperi
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
metastasis
epigenetics
histone modifications
EMT
acetylation
methylation
Online Access:https://www.mdpi.com/1422-0067/22/5/2778

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