Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy

Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Signif...

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Main Authors: N. B. Gubanova, Yu. V. Karakulova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2008-12-01
Series:Bûlleten' Sibirskoj Mediciny
Online Access:https://bulletin.tomsk.ru/jour/article/view/3446
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spelling doaj-b471bb559ea74906848cf9fc03a16e422021-07-29T08:37:47ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842008-12-0175-1878910.20538/1682-0363-2008-5-1-87-892093Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsyN. B. Gubanova0Yu. V. Karakulova1Пермская государственная медицинская академияПермская государственная медицинская академияNeurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method.https://bulletin.tomsk.ru/jour/article/view/3446
collection DOAJ
language English
format Article
sources DOAJ
author N. B. Gubanova
Yu. V. Karakulova
spellingShingle N. B. Gubanova
Yu. V. Karakulova
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
Bûlleten' Sibirskoj Mediciny
author_facet N. B. Gubanova
Yu. V. Karakulova
author_sort N. B. Gubanova
title Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
title_short Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
title_full Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
title_fullStr Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
title_full_unstemmed Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
title_sort pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
publisher Siberian State Medical University (Tomsk)
series Bûlleten' Sibirskoj Mediciny
issn 1682-0363
1819-3684
publishDate 2008-12-01
description Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method.
url https://bulletin.tomsk.ru/jour/article/view/3446
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