Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Signif...
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Siberian State Medical University (Tomsk)
2008-12-01
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Series: | Bûlleten' Sibirskoj Mediciny |
Online Access: | https://bulletin.tomsk.ru/jour/article/view/3446 |
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doaj-b471bb559ea74906848cf9fc03a16e422021-07-29T08:37:47ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842008-12-0175-1878910.20538/1682-0363-2008-5-1-87-892093Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsyN. B. Gubanova0Yu. V. Karakulova1Пермская государственная медицинская академияПермская государственная медицинская академияNeurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method.https://bulletin.tomsk.ru/jour/article/view/3446 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
N. B. Gubanova Yu. V. Karakulova |
spellingShingle |
N. B. Gubanova Yu. V. Karakulova Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy Bûlleten' Sibirskoj Mediciny |
author_facet |
N. B. Gubanova Yu. V. Karakulova |
author_sort |
N. B. Gubanova |
title |
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
title_short |
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
title_full |
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
title_fullStr |
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
title_full_unstemmed |
Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
title_sort |
pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
publisher |
Siberian State Medical University (Tomsk) |
series |
Bûlleten' Sibirskoj Mediciny |
issn |
1682-0363 1819-3684 |
publishDate |
2008-12-01 |
description |
Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method. |
url |
https://bulletin.tomsk.ru/jour/article/view/3446 |
work_keys_str_mv |
AT nbgubanova pathogenicalmeaningofserotoninergicmechanismsinthedevelopmentofidiopaticgeneralisedformsofepilepsy AT yuvkarakulova pathogenicalmeaningofserotoninergicmechanismsinthedevelopmentofidiopaticgeneralisedformsofepilepsy |
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1721253850257555456 |