Oxidative stress in the developing brain: effects of postnatal glucocorticoid therapy and antioxidants in the rat.

Oxidative stress in the developing brain: effects of postnatal glucocorticoid therapy and antioxidants in the rat.

In premature infants, glucocorticoids ameliorate chronic lung disease, but have adverse effects on long-term neurological function. Glucocorticoid excess promotes free radical overproduction. We hypothesised that the adverse effects of postnatal glucocorticoid therapy on the developing brain are sec...

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Bibliographic Details
Main Authors: Emily J Camm, Deodata Tijsseling, Hans G Richter, Alexandra Adler, Jeremy A Hansell, Jan B Derks, Christine M Cross, Dino A Giussani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3115992?pdf=render

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