Substantial underestimation of SARS-CoV-2 infection in the United States

Estimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.

Bibliographic Details
Main Authors:	Sean L. Wu, Andrew N. Mertens, Yoshika S. Crider, Anna Nguyen, Nolan N. Pokpongkiat, Stephanie Djajadi, Anmol Seth, Michelle S. Hsiang, John M. Colford, Art Reingold, Benjamin F. Arnold, Alan Hubbard, Jade Benjamin-Chung
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-18272-4

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spelling	doaj-b446f7b11c1a46e3b5ae78349ccb4b332021-09-12T11:48:57ZengNature Publishing GroupNature Communications2041-17232020-09-0111111010.1038/s41467-020-18272-4Substantial underestimation of SARS-CoV-2 infection in the United StatesSean L. Wu0Andrew N. Mertens1Yoshika S. Crider2Anna Nguyen3Nolan N. Pokpongkiat4Stephanie Djajadi5Anmol Seth6Michelle S. Hsiang7John M. Colford8Art Reingold9Benjamin F. Arnold10Alan Hubbard11Jade Benjamin-Chung12Division of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDepartment of Pediatrics, University of Texas Southwestern Medical CenterDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaFrancis I. Proctor Foundation, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaEstimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.https://doi.org/10.1038/s41467-020-18272-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sean L. Wu Andrew N. Mertens Yoshika S. Crider Anna Nguyen Nolan N. Pokpongkiat Stephanie Djajadi Anmol Seth Michelle S. Hsiang John M. Colford Art Reingold Benjamin F. Arnold Alan Hubbard Jade Benjamin-Chung
spellingShingle	Sean L. Wu Andrew N. Mertens Yoshika S. Crider Anna Nguyen Nolan N. Pokpongkiat Stephanie Djajadi Anmol Seth Michelle S. Hsiang John M. Colford Art Reingold Benjamin F. Arnold Alan Hubbard Jade Benjamin-Chung Substantial underestimation of SARS-CoV-2 infection in the United States Nature Communications
author_facet	Sean L. Wu Andrew N. Mertens Yoshika S. Crider Anna Nguyen Nolan N. Pokpongkiat Stephanie Djajadi Anmol Seth Michelle S. Hsiang John M. Colford Art Reingold Benjamin F. Arnold Alan Hubbard Jade Benjamin-Chung
author_sort	Sean L. Wu
title	Substantial underestimation of SARS-CoV-2 infection in the United States
title_short	Substantial underestimation of SARS-CoV-2 infection in the United States
title_full	Substantial underestimation of SARS-CoV-2 infection in the United States
title_fullStr	Substantial underestimation of SARS-CoV-2 infection in the United States
title_full_unstemmed	Substantial underestimation of SARS-CoV-2 infection in the United States
title_sort	substantial underestimation of sars-cov-2 infection in the united states
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-09-01
description	Estimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.
url	https://doi.org/10.1038/s41467-020-18272-4
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Substantial underestimation of SARS-CoV-2 infection in the United States

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