The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig

Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.

Bibliographic Details
Main Author: B. Djahanguiri
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1970-12-01
Series:Acta Medica Iranica
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4116
id doaj-b43911f8b5f543dcbd19537cc59ce3d4
record_format Article
spelling doaj-b43911f8b5f543dcbd19537cc59ce3d42020-11-25T03:47:58ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96941970-12-013-4The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig B. Djahanguiri0 Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed. https://acta.tums.ac.ir/index.php/acta/article/view/4116
collection DOAJ
language English
format Article
sources DOAJ
author B. Djahanguiri
spellingShingle B. Djahanguiri
The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
Acta Medica Iranica
author_facet B. Djahanguiri
author_sort B. Djahanguiri
title The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
title_short The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
title_full The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
title_fullStr The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
title_full_unstemmed The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
title_sort inhibitory effect of acetazoleamide on indomethacin-induced gastric ulcer in guinea pig
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 1970-12-01
description Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.
url https://acta.tums.ac.ir/index.php/acta/article/view/4116
work_keys_str_mv AT bdjahanguiri theinhibitoryeffectofacetazoleamideonindomethacininducedgastriculceringuineapig
AT bdjahanguiri inhibitoryeffectofacetazoleamideonindomethacininducedgastriculceringuineapig
_version_ 1724500936928264192