Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

Abstract Background Detection of cholangiocarcinoma (CCA) remains a diagnostic challenge. We established diagnostic peptide biomarkers in bile and urine based on capillary electrophoresis coupled to mass spectrometry (CE-MS) to detect both local and systemic changes during CCA progression. In a pros...

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Bibliographic Details
Main Authors: Torsten Voigtländer, Jochen Metzger, Holger Husi, Martha M. Kirstein, Martin Pejchinovski, Agnieszka Latosinska, Maria Frantzi, William Mullen, Thorsten Book, Harald Mischak, Michael P. Manns
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Cholangiocarcinoma
Biomarkers
Biomolecular pathways
Proteomics
Online Access:https://doi.org/10.1186/s12929-019-0599-5

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