In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics
Directing nanomedicines to desired locations - such as tumour sites - is difficult to achieve selectively. Here, the authors develop a method to covalently crosslink peptide-modified upconversion nanocrystals into tumour sites for photodynamic therapy and show in vivotumour inhibition in mice.
Main Authors: | Xiangzhao Ai, Chris Jun Hui Ho, Junxin Aw, Amalina Binte Ebrahim Attia, Jing Mu, Yu Wang, Xiaoyong Wang, Yong Wang, Xiaogang Liu, Huabing Chen, Mingyuan Gao, Xiaoyuan Chen, Edwin K.L. Yeow, Gang Liu, Malini Olivo, Bengang Xing |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10432 |
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