Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

DNA three-way junctions are branched structures formed during replication, repair, and recombination, and are involved in models of repeat expansion. Here the authors use single-molecule Förster resonance energy transfer to reveal the dynamics of DNA three-way junctions containing slip-outs composed...

Full description

Bibliographic Details
Main Authors: Tianyu Hu, Michael J. Morten, Steven W. Magennis
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20426-3
id doaj-b4270191136b440cbcca6eb5e6840989
record_format Article
spelling doaj-b4270191136b440cbcca6eb5e68409892021-01-10T12:18:58ZengNature Publishing GroupNature Communications2041-17232021-01-011211810.1038/s41467-020-20426-3Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeatsTianyu Hu0Michael J. Morten1Steven W. Magennis2School of Chemistry, University of GlasgowSchool of Chemistry, University of GlasgowSchool of Chemistry, University of GlasgowDNA three-way junctions are branched structures formed during replication, repair, and recombination, and are involved in models of repeat expansion. Here the authors use single-molecule Förster resonance energy transfer to reveal the dynamics of DNA three-way junctions containing slip-outs composed of CAG or CTG repeats.https://doi.org/10.1038/s41467-020-20426-3
collection DOAJ
language English
format Article
sources DOAJ
author Tianyu Hu
Michael J. Morten
Steven W. Magennis
spellingShingle Tianyu Hu
Michael J. Morten
Steven W. Magennis
Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
Nature Communications
author_facet Tianyu Hu
Michael J. Morten
Steven W. Magennis
author_sort Tianyu Hu
title Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
title_short Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
title_full Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
title_fullStr Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
title_full_unstemmed Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
title_sort conformational and migrational dynamics of slipped-strand dna three-way junctions containing trinucleotide repeats
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-01-01
description DNA three-way junctions are branched structures formed during replication, repair, and recombination, and are involved in models of repeat expansion. Here the authors use single-molecule Förster resonance energy transfer to reveal the dynamics of DNA three-way junctions containing slip-outs composed of CAG or CTG repeats.
url https://doi.org/10.1038/s41467-020-20426-3
work_keys_str_mv AT tianyuhu conformationalandmigrationaldynamicsofslippedstranddnathreewayjunctionscontainingtrinucleotiderepeats
AT michaeljmorten conformationalandmigrationaldynamicsofslippedstranddnathreewayjunctionscontainingtrinucleotiderepeats
AT stevenwmagennis conformationalandmigrationaldynamicsofslippedstranddnathreewayjunctionscontainingtrinucleotiderepeats
_version_ 1714951790907097088

Similar Items