Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure–activity relationship (QSAR) method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfu...

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Bibliographic Details
Main Authors:	Yong-Hong Zhang, Zhi-Ning Xia, Li Yan, Shu-Shen Liu
Format:	Article
Language:	English
Published:	MDPI AG 2015-05-01
Series:	Molecules
Subjects:	placental barrier permeability descriptors based on Dragon software PLS regression variable importance in projection (VIP) validation application domain
Online Access:	http://www.mdpi.com/1420-3049/20/5/8270

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