Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure
Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure–activity relationship (QSAR) method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-05-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/5/8270 |