A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis.
Tissue fibrosis is a significant health issue associated with organ dysfunction and failure. Increased deposition of collagen and other extracellular matrix (ECM) proteins in the interstitial area is a major process in tissue fibrosis. The microRNA-29 (miR-29) family has been demonstrated as anti-fi...
Main Authors: | Xiaoming Fan, Yingnyu Gao, Xiaolu Zhang, Haroon Y Lughmani, David J Kennedy, Steven T Haller, Sandrine V Pierre, Joseph I Shapiro, Jiang Tian |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0244065 |
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