The cellular prion protein interacts with the tissue non-specific alkaline phosphatase in membrane microdomains of bioaminergic neuronal cells.

The cellular prion protein interacts with the tissue non-specific alkaline phosphatase in membrane microdomains of bioaminergic neuronal cells.

BACKGROUND: The cellular prion protein, PrP(C), is GPI anchored and abundant in lipid rafts. The absolute requirement of PrP(C) in neurodegeneration associated to prion diseases is well established. However, the function of this ubiquitous protein is still puzzling. Our previous work using the 1C11...

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Main Authors: Myriam Ermonval, Anne Baudry, Florence Baychelier, Elodie Pradines, Mathéa Pietri, Kimimitsu Oda, Benoît Schneider, Sophie Mouillet-Richard, Jean-Marie Launay, Odile Kellermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2715859?pdf=render

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http://europepmc.org/articles/PMC2715859?pdf=render

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