Metronidazole Induced Cerebellar Toxicity: A Case Report

Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We pr...

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Bibliographic Details
Main Authors: Shova Sapkota, Aliska Niroula, Rina Prajapati, Subhani Sharma, Krishna Dhungana
Format: Article
Language:English
Published: Nepal Medical Association 2021-09-01
Series:Journal of Nepal Medical Association
Subjects:
Online Access:https://www.jnma.com.np/jnma/index.php/jnma/article/view/6644
Description
Summary:Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.
ISSN:0028-2715
1815-672X